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Validation of the BrockTB stat-pak assay for detection of tuberculosis in Eurasian badgers (Meles meles) and influence of disease severity on diagnostic accuracy.

Chambers MA, Crawshaw T, Waterhouse S, Delahay R, Hewinson RG, Lyashchenko KP

TB Research Group, Department of Statutory and Exotic Bacterial Diseases, Veterinary Laboratories Agency Weybridge, New Haw, Surrey KT15 3NB, United Kingdom. m.a.chambers@vla.defra.gsi.gov.uk.

A lateral-flow immunoassay (BrockTB Stat-Pak) for detecting tuberculosis in Eurasian badgers was 49% sensitive and 93% specific against culture for M. bovis (n = 1,464) at necropsy. However, the sensitivity was significantly higher (66 to 78%) in animals with more severe tuberculosis, indicating that the BrockTB Stat-Pak may be useful for the detection of badgers with the greatest risk of transmitting disease.

Published 4 April 2008 in J Clin Microbiol, 46(4): 1498-500.
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