Tuberculosis Research Today is a free monthly online journal that collates and summarizes the latest research about Tuberculosis, including details on symptoms, causes, treatment, pulmonary, mycobacterium.

Disseminated Mycobacterium tuberculosis infection due to interferon gamma deficiency. Response to replacement therapy.

Luke Seneviratne S, Doffinger R, Macfarlane J, Ceron-Gutierrez L, Amel Kashipaz MR, Robbins A, Patel T, Powell PT, Kumararatne DS, Powell RJ

Clinical Immunology Unit, Queens Medical Centre, Nottingham, UK. suran200@yahoo.co.uk

The case of a previously healthy HIV seronegative woman with disseminated Mycobacterium tuberculosis infection and markedly reduced interferon gamma production is reported here. Complete healing of her disseminated lesions was seen only after addition of subcutaneous interferon gamma to her tuberculosis treatment.

Published 25 December 2006 in Thorax, 62(1): 97-9.
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